Diagnostic Enhancement of Screening Mammograms by Means of Local Texture Models

   Jiří Grim    Petr Somol    Michal Haindl    Jan Daneš
Abstract: 
Statistically based preprocessing of screening mammograms is proposed with the aim to in-crease the diagnostic conspicuity of mammographic lesions. We estimate first the local statis-tical texture model of a single mammogram as a joint probability density of grey levels in a suitably chosen search window. The probability density in the form of multivariate Gaussian mixture is estimated from data obtained by pixel-wise scanning the mammogram with the search window. In the second phase we evaluate the estimated density at each position of the window and display the corresponding log-likelihood value as grey level at window center. Light grey levels correspond to the typical parts of the image and the dark values reflect unusual places. The resulting log-likelihood image closely correlates with fine structural details of the original mammogram and facilitates diagnostic interpretation of suspect abnormalities.

 

Sample Results

B_3017_1
B_3017_1  Ground Truth   B_3017_1  Original   B_3017_1  Processed
Ground Truth Original Processed
Left MLO: Lesion type: mass, lobulated shape, ill-defined margins.
Left CC: Lesion type: mass, shape: lobulated-architectural distortion, microlobulated-spiculated margins.
 
B_3020_1
B_3020_1  Ground Truth   B_3020_1  Original   B_3020_1  Processed
Ground Truth Original Processed
Right MLO: Lesion type: mass, lobulated shape, circumscribed-ill defined margins.
Right CC: Lesion type: mass, lobulated shape, circumscribed-ill defined margins.
 
B_3056_1
B_3056_1  Ground Truth   B_3056_1  Original   B_3056_1  Processed
Ground Truth Original Processed
Left MLO: Lesion type: mass, shape: focal-asymmetric density, margins n/a.
Left CC: Lesion type: mass, shape: focal-asymmetric density, margins n/a.
 
C_0001_1
C_0001_1  Ground Truth   C_0001_1  Original   C_0001_1  Processed
Ground Truth Original Processed
Right MLO: Lesion type: mass, irregular shape, spiculated margins.
Right CC: Lesion type: mass, irregular shape,